Enzyme Details

Enzyme (Recommended) Name	squalene synthase
Alternative names	farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase farnesyltransferase presqualene-diphosphate synthase presqualene synthase squalene synthetase farnesyl-diphosphate farnesyltransferase SQS
EC Classification	2.5.1.21
Classification	Transferases Transferring alkyl or aryl groups, other than methyl groups Transferring alkyl or aryl groups, other than methyl groups
Catalyses reactions	2 trans,trans-Farnesyl diphosphate <-> H+ + Diphosphate + Presqualene diphosphate H+ + NADPH + Presqualene diphosphate <-> NADP+ + Diphosphate + Squalene H+ + NADPH + 2 trans,trans-Farnesyl diphosphate <-> NADP+ + 2 Diphosphate + Squalene
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 2.5.1.21