Enzyme Details

Enzyme (Recommended) Name	deoxyhypusine synthase
Alternative names	[eIF5A-precursor]-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming)
EC Classification	2.5.1.46
Classification	Transferases Transferring alkyl or aryl groups, other than methyl groups Transferring alkyl or aryl groups, other than methyl groups
Catalyses reactions	Putrescine + Spermidine <-> 1,3-Diaminopropane + Homospermidine Spermidine + [eIF5A-precursor]-lysine <-> 1,3-Diaminopropane + [eIF5A-precursor]-deoxyhypusine Putrescine + Homospermidine <-> Putrescine + Homospermidine Putrescine + [eIF5A-precursor]-deoxyhypusine <-> Homospermidine + [eIF5A-precursor]-lysine
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 2.5.1.46