Enzyme Details

Enzyme (Recommended) Name	hydroxymethylbilane synthase
Alternative names	porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing) HMB-synthase porphobilinogen deaminase pre-uroporphyrinogen synthase uroporphyrinogen I synthase uroporphyrinogen I synthetase uroporphyrinogen synthase uroporphyrinogen synthetase porphobilinogen ammonia-lyase (polymerizing) (4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)
EC Classification	2.5.1.61
Classification	Transferases Transferring alkyl or aryl groups, other than methyl groups Transferring alkyl or aryl groups, other than methyl groups
Catalyses reactions	H2O + 4 Porphobilinogen <-> 4 NH3 + Hydroxymethylbilane
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 2.5.1.61