Enzyme Details

Enzyme (Recommended) Name	aspartate transaminase
Alternative names	L-aspartate:2-oxoglutarate aminotransferase glutamic-oxaloacetic transaminase glutamic-aspartic transaminase transaminase A AAT AspT 2-oxoglutarate-glutamate aminotransferase aspartate alpha-ketoglutarate transaminase aspartate aminotransferase aspartate-2-oxoglutarate transaminase aspartic acid aminotransferase aspartic aminotransferase aspartyl aminotransferase AST glutamate-oxalacetate aminotransferase glutamate-oxalate transaminase glutamic-aspartic aminotransferase glutamic-oxalacetic transaminase glutamic oxalic transaminase GOT (enzyme) L-aspartate transaminase L-aspartate-alpha-ketoglutarate transaminase L-aspartate-2-ketoglutarate aminotransferase L-aspartate-2-oxoglutarate aminotransferase L-aspartate-2-oxoglutarate-transaminase L-aspartic aminotransferase oxaloacetate-aspartate aminotransferase oxaloacetate transferase aspartate:2-oxoglutarate aminotransferase glutamate oxaloacetate transaminase
EC Classification	2.6.1.1
Classification	Transferases Transferring nitrogenous groups Transaminases (aminotransferases)
Catalyses reactions	L-Alanine + 2-Oxoglutarate <-> Pyruvate + L-Glutamate L-Aspartate + 2-Oxoglutarate <-> L-Glutamate + Oxaloacetate L-Tryptophan + 2-Oxoglutarate <-> L-Glutamate + Indolepyruvate L-Phenylalanine + 2-Oxoglutarate <-> L-Glutamate + Phenylpyruvate L-Tyrosine + 2-Oxoglutarate <-> L-Glutamate + 3-(4-Hydroxyphenyl)pyruvate L-Cysteine + 2-Oxoglutarate <-> Glutamate + 3-Mercaptopyruvate L-Leucine + 2-Oxoglutarate <-> L-Glutamate + 4-Methyl-2-oxopentanoate 2-Oxoglutarate + L-Cysteate <-> Glutamate + 3-Sulfopyruvate 2-Oxoglutarate + 3-Sulfino-L-alanine <-> Glutamate + 3-Sulfinylpyruvate 2-Oxoglutarate + L-erythro-4-Hydroxyglutamate <-> L-Glutamate + D-4-Hydroxy-2-oxoglutarate Oxaloacetate + L-Arogenate <-> L-Aspartate + Prephenate 2-Oxoglutarate + L-Arogenate <-> L-Glutamate + Prephenate 2-Oxoglutarate + L-2-Amino-4-methoxy-4-oxobutanoic acid <-> L-Glutamate + 2-Oxo-4-methoxy-4-oxobutanoic acid
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 2.6.1.1