Enzyme Details

Enzyme (Recommended) Name	thymidine kinase
Alternative names	ATP:thymidine 5'-phosphotransferase thymidine kinase (phosphorylating) 2'-deoxythymidine kinase deoxythymidine kinase (phosphorylating)
EC Classification	2.7.1.21
Classification	Transferases Transferring phosphorous-containing groups Phosphotransferases with an alcohol group as acceptor
Catalyses reactions	ATP + Thymidine <-> ADP + dTMP ATP + 2'-Deoxycytidine <-> ADP + dCMP ATP + 2'-Deoxyuridine <-> ADP + dUMP ATP + Ganciclovir <-> ADP + Ganciclovir phosphate ATP + Acyclovir <-> ADP + Acyclovir monophosphate ATP + Zidovudine <-> ADP + 3'-Azido-3'-deoxythymidine 5'-phosphate Thymidine + dTTP <-> dTMP + TDP CTP + Thymidine <-> dTMP + CDP GTP + Thymidine <-> dTMP + GDP ATP + 1-beta-D-Arabinofuranosylthymine <-> ADP + 1-beta-D-Arabinofuranosylthymine 5'-monophosphate ATP + 3'-Azido-2',3'-dideoxythymidine <-> ADP + 3'-Azido-2',3'-dideoxythymidine 5'-phosphate ATP + 3'-Fluoro-2',3'-dideoxythymidine <-> ADP + 3'-Fluoro-2',3'-dideoxythymidine 5'-phosphate ATP + 5-Fluorodeoxyuridine <-> ADP + 5-Fluorodeoxyuridine 5'-phosphate CTP + 2'-Deoxycytidine <-> dCMP + CDP 2 Thymidine + VVTK <-> Enzyme-ligand complex Thymidine + HSV-1 TK <-> Enzyme-ligand complex
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 2.7.1.21