Enzyme Details

Enzyme (Recommended) Name	sphingomyelin phosphodiesterase
Alternative names	sphingomyelin cholinephosphohydrolase neutral sphingomyelinase
EC Classification	3.1.4.12
Classification	Hydrolases Acting on ester bonds Phosphoric diester hydrolases
Catalyses reactions	H2O + Sphingomyelin <-> Choline phosphate + N-Acylsphingosine H2O + 1-O-Hexadecyl-lyso-sn-glycero-3-phosphocholine <-> Choline phosphate + 1-O-Hexadecyl-sn-glycerol H2O + Arachidoyllysophosphatidylcholine <-> Choline phosphate + Monoarachidin H2O + Myristoyllysophosphatidylcholine <-> Choline phosphate + Monomyristin H2O + Palmitoyllysophosphatidylcholine <-> Choline phosphate + Monopalmitin H2O + Stearoyllysophosphatidylcholine <-> Choline phosphate + Monostearin
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 3.1.4.12