Enzyme Details

Enzyme (Recommended) Name	leukotriene-A4 hydrolase
Alternative names	(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase LTA4 hydrolase LTA4H leukotriene A4 hydrolase
EC Classification	3.3.2.6
Classification	Hydrolases Acting on ether bonds Ether hydrolases
Catalyses reactions	H2O + Leukotriene A4 <-> Leukotriene B4 H2O + Leukotriene A4 <-> 5S,6S-Dihydroxy-7,9-trans-11,14-cis-eicosatetraenoic acid H2O + L-Leucinyl-p-nitroanilide <-> L-Leucine + 4-Nitroaniline H2O + L-Methionine-p-nitroanilide <-> L-Methionine + 4-Nitroaniline H2O + L-Alanyl-p-nitroanilide <-> L-Alanine + 4-Nitroaniline H2O + L-Arginyl-p-nitroanilide <-> L-Arginine + 4-Nitroaniline H2O + Prolyl-p-nitroanilide <-> 4-Nitroaniline + Proline H2O + L-Lysyl-p-nitroanilide <-> L-Lysine + 4-Nitroaniline H2O + Ala-p-nitroanilide <-> Alanine + 4-Nitroaniline
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 3.3.2.6