Enzyme Details

Enzyme (Recommended) Name	leukocyte elastase
Alternative names	lysosomal elastase neutrophil elastase polymorphonuclear leukocyte elastase elastase elaszym serine elastase lysosomal elastase granulocyte elastase
EC Classification	3.4.21.37
Classification	Hydrolases Acting on peptide bonds (peptide hydrolases) Serine endopeptidases
Catalyses reactions	H2O + Succinyl-Ala-Ala-Val-p-nitroanilide <-> 4-Nitroaniline + Succinyl-Ala-Ala-Val H2O + N-tert-Butoxycarbonyl-L-alanine p-nitrophenyl ester <-> N-tert-Butoxycarbonyl-L-alanine + Nitrophenol H2O + N-Succinyl-Ala-Ala-Ala-p-nitroanilide <-> 4-Nitroaniline + N-Succinyl-Ala-Ala-Ala H2O + Succinyl-Ala-Ala-Pro-Val-7-(4-methyl)coumarylamide <-> Succinyl-Ala-Ala-Pro-Val + 7-Amino-4-methylcoumarin H2O + Methoxysuccinyl-Ala-Ala-Pro-Val-7-(4-methyl)coumarylamide <-> Methoxysuccinyl-Ala-Ala-Pro-Val + 7-Amino-4-methylcoumarin H2O + Methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide <-> 4-Nitroaniline + Methoxysuccinyl-Ala-Ala-Pro-Val H2O + Methoxysuccinyl-Lys(2-picolinoyl)-Ala-Pro-Val-4-nitroanilide <-> 4-Nitroaniline + Methoxysuccinyl-Lys(2-picolinoyl)-Ala-Pro-Val
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 3.4.21.37