Enzyme Details

Enzyme (Recommended) Name	aromatic-L-amino-acid decarboxylase
Alternative names	aromatic-L-amino-acid carboxy-lyase DOPA decarboxylase tryptophan decarboxylase hydroxytryptophan decarboxylase L-DOPA decarboxylase aromatic amino acid decarboxylase 5-hydroxytryptophan decarboxylase aromatic-L-amino-acid carboxy-lyase (tryptamine-forming)
EC Classification	4.1.1.28
Classification	Lyases Carbon-carbon lyases carboxy-lyases
Catalyses reactions	L-Tryptophan <-> CO2 + Tryptamine L-Phenylalanine <-> CO2 + 2-Phenylethylamine L-Tyrosine <-> CO2 + Tyramine L-Histidine <-> CO2 + Histamine L-Dopa <-> CO2 + Dopamine 5-Hydroxy-L-tryptophan <-> CO2 + Serotonin CO2 + 5-Hydroxykynurenamine <-> 5-Hydroxykynurenine Pyridoxal phosphate + apo-DDC <-> holo-DDC L-Dopa + holo-DDC <-> Enzyme-ligand complex D-Dopa + holo-DDC <-> Enzyme-ligand complex 3,4-Dihydroxyphenylacetate + AADC <-> Enzyme-ligand complex AADC + L-Dopa methyl ester <-> Enzyme-ligand complex
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 4.1.1.28