Enzyme Details

Enzyme (Recommended) Name	tartronate-semialdehyde synthase
Alternative names	glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming) tartronate semialdehyde carboxylase glyoxylate carbo-ligase glyoxylic carbo-ligase hydroxymalonic semialdehyde carboxylase tartronic semialdehyde carboxylase glyoxalate carboligase glyoxylate carboxy-lyase (dimerizing)
EC Classification	4.1.1.47
Classification	Lyases Carbon-carbon lyases carboxy-lyases
Catalyses reactions	2 Glyoxylate <-> CO2 + 2-Hydroxy-3-oxopropanoate Thiamine diphosphate + Acetylphosphinate + GCL <-> GCL-1',4'-iminophosphinolactylThDP Thiamine diphosphate + Acetylphosphinate + GCL <-> GCL-ThDP-ligand complex Thiamine diphosphate + Methylacetylphosphonate + GCL <-> GCL-1',4'-iminophosphonolactylThDP Thiamine diphosphate + Methylacetylphosphonate + GCL <-> GCL-ThDP-ligand complex Thiamine diphosphate + GCL + Propionylphosphinate <-> GCL-1',4'-iminophosphinopropionylThDP Thiamine diphosphate + GCL + Propionylphosphinate <-> GCL-1',4'-iminophosphinolactylThDP Thiamine diphosphate + Methylacetylphosphonate + GCL <-> GCL-1',4'-iminophosphinolactylThDP
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 4.1.1.47