Enzyme Details

Enzyme (Recommended) Name	cystathionine beta-synthase
Alternative names	L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming) serine sulfhydrase beta-thionase methylcysteine synthase cysteine synthase serine sulfhydrylase L-serine hydro-lyase (adding homocysteine)
EC Classification	4.2.1.22
Classification	Lyases Carbon-oxygen lyases Hydro-lyases
Catalyses reactions	L-Serine <-> Pyruvate + NH3 L-Serine + Sulfide <-> H2O + L-Cysteine H2O + L-Cystathionine <-> Pyruvate + NH3 + L-Homocysteine L-Serine + L-Homocysteine <-> H2O + Cystathionine L-Serine + L-Homocysteine <-> H2O + L-Cystathionine L-Serine + Selenohomocysteine <-> H2O + Selenocystathionine L-Cysteine + L-Homocysteine <-> Hydrogen sulfide + L-Cystathionine O-Acetyl-L-serine + Sulfide <-> L-Cysteine + Acetate L-Cysteine + 2-Mercaptoethanol <-> Hydrogen sulfide + S-(2-Hydroxyethyl)-L-cysteine
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 4.2.1.22