Enzyme Details

Enzyme (Recommended) Name	homoaconitate hydratase
Alternative names	(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(Z)-but-1-ene-1,2,4-tricarboxylate-forming] homoaconitase cis-homoaconitase HACN Lys4 LysF 2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase (incorrect)
EC Classification	4.2.1.36
Classification	Lyases Carbon-oxygen lyases Hydro-lyases
Catalyses reactions	D-Malate <-> H2O + Maleate Homocitrate <-> H2O + But-1-ene-1,2,4-tricarboxylate Homoisocitrate <-> H2O + But-1-ene-1,2,4-tricarboxylate H2O + cis-Homo(2)-aconitate <-> Homo(2)-citrate H2O + cis-Homo(3)-aconitate <-> Homo(3)-citrate H2O + cis-Homo(4)-aconitate <-> Homo(4)-citrate H2O + cis-Homo(2)-aconitate <-> Homo(2)-isocitrate H2O + cis-Homo(3)-aconitate <-> Homo(3)-isocitrate H2O + cis-Homo(4)-aconitate <-> Homo(4)-isocitrate
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 4.2.1.36