Enzyme Details

Enzyme (Recommended) Name	6-pyruvoyltetrahydropterin synthase
Alternative names	7,8-dihydroneopterin 3'-triphosphate triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming) 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming)
EC Classification	4.2.3.12
Classification	Lyases Carbon-oxygen lyases Acting on phosphates
Catalyses reactions	H2O + 7,8-Dihydroneopterin 3'-triphosphate <-> Triphosphate + 6-Pyruvoyltetrahydropterin 3 H2O + 2-Amino-4-oxo-6-(erythro-1',2',3'-trihydroxypropyl)-7,8-dihydroxypteridine triphosphate <-> 3 Phosphate + 2-Amino-4-oxo-6-(1',2'-dioxoprolyl)-7,8-dihydroxypteridine 7,8-Dihydroneopterin 3'-triphosphate <-> Triphosphate + 6-Pyruvoyltetrahydropterin
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 4.2.3.12