Enzyme Details

Enzyme (Recommended) Name	methionine gamma-lyase
Alternative names	L-methionine methanethiol-lyase (deaminating; 2-oxobutanoate-forming) L-methioninase methionine lyase methioninase methionine dethiomethylase L-methionine gamma-lyase L-methionine methanethiol-lyase (deaminating)
EC Classification	4.4.1.11
Classification	Lyases Carbon-sulfur lyases Carbon-sulfur lyases
Catalyses reactions	H2O + L-Methionine <-> NH3 + 2-Oxobutyrate + Methanethiol H2O + L-Cysteine <-> Pyruvate + NH3 + Hydrogen sulfide H2O + Selenomethionine <-> NH3 + 2-Oxobutyrate + Methaneselenol H2O + O-Acetyl-L-serine <-> Pyruvate + NH3 + Acetate H2O + Homocysteine <-> NH3 + 2-Oxobutyrate + Hydrogen sulfide H2O + Trifluoromethionine <-> NH3 + 2-Oxobutyrate + Trifluoromethanethiol
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 4.4.1.11