Enzyme Details

Enzyme (Recommended) Name	cysteine-S-conjugate beta-lyase
Alternative names	L-cysteine-S-conjugate thiol-lyase (deaminating; pyruvate-forming) cysteine conjugate beta-lyase glutamine transaminase K/cysteine conjugate beta-lyase L-cysteine-S-conjugate thiol-lyase (deaminating) S-alkylcysteine lyase S-alkyl-L-cysteine alkyl-thiol-lyase (deaminating; pyruvate-forming) S-alkylcysteinase alkylcysteine lyase S-alkyl-L-cysteine sulfoxide lyase S-alkyl-L-cysteine lyase S-alkyl-L-cysteinase alkyl cysteine lyase S-alkyl-L-cysteine alkylthiol-lyase (deaminating) cystathionine beta-lyase L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming) beta-cystathionase cystine lyase cystathionine L-homocysteine-lyase (deaminating) L-cystathionine L-homocysteine-lyase (deaminating)
EC Classification	4.4.1.13
Classification	Lyases Carbon-sulfur lyases Carbon-sulfur lyases
Catalyses reactions	Cl- + Pyruvate + NH3 <-> H2O + 3-Chloro-L-alanine H2O + RS-CH2-CH(NH3+)COO- <-> Pyruvate + NH3 + RSH H2O + S-(1,1,2,2-Tetrafluoroethyl)-L-cysteine <-> Pyruvate + NH3 + 1,1,2,2-Tetrafluoroethanethiol H2O + S-(1,2-Dichlorovinyl)-L-cysteine <-> Pyruvate + NH3 + S-(1,2-Dichlorovinyl)thiol H2O + L-Cysteine <-> Pyruvate + NH3 + Hydrogen sulfide H2O + Cystathionine <-> Pyruvate + NH3 + L-Homocysteine H2O + L-Cystathionine <-> Pyruvate + NH3 + L-Homocysteine H2O + L-Cystine <-> Pyruvate + NH3 + Thiocysteine H2O + S-Alkyl-L-cysteine <-> Pyruvate + NH3 + Alkyl thiol H2O + Selenocystathionine <-> Pyruvate + NH3 + Selenohomocysteine H2O + S-Methyl-L-cysteine <-> Pyruvate + NH3 + Methanethiol H2O + S-Ethyl-L-cysteine <-> Pyruvate + NH3 + Ethanethiol H2O + Meso-Cystine <-> Pyruvate + NH3 + 3-Disulfanyl-D-alanine H2O + Desaminocystine <-> Pyruvate + NH3 + 3-Disulfanylpropanoic acid H2O + L-Djenkolic acid <-> Pyruvate + NH3 + 2-Amino-3-(sulfanylmethylsulfanyl)propanoic acid H2O + Decarboxycystine <-> NH3 + Acetaldehyde + 2-Disulfanylethanamine H2O + L-Djenkolic acid <-> Pyruvate + NH3 + 2-Amino-3-(sulfanylmethylsulfanyl)propanoic acid H2O + L-Selenodjenkolate <-> Pyruvate + NH3 + Se-(Hydroselenomethyl)selenocysteine H2O + S-Methyl-L-cysteine <-> Pyruvate + NH3 + Methanethiol H2O + Se-Methyl-L-selenocysteine <-> Unknown + Pyruvate + NH3 H2O + O-Methylserine <-> Pyruvate + Methanol + NH3 H2O + S-Ethyl-L-cysteine <-> Pyruvate + NH3 + Ethanethiol H2O + S-Benzyl-L-cysteine <-> Pyruvate + NH3 + Benzylthiol H2O + S-Carboxymethyl-L-cysteine <-> Pyruvate + NH3 + Thioglycolate H2O + L-Cysteine <-> Pyruvate + NH3 + Hydrogen sulfide H2O + L-Cystathionine <-> Pyruvate + NH3 + L-Homocysteine H2O + Lanthionine <-> Pyruvate + L-Cysteine + NH3
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 4.4.1.13