Enzyme Details

Enzyme (Recommended) Name	butyrate---CoA ligase
Alternative names	butanoate:CoA ligase (AMP-forming) butyryl-CoA synthetase fatty acid thiokinase (medium chain) acyl-activating enzyme fatty acid elongase fatty acid activating enzyme fatty acyl coenzyme A synthetase medium chain acyl-CoA synthetase butyryl-coenzyme A synthetase L-(+)-3-hydroxybutyryl CoA ligase short-chain acyl-CoA synthetase
EC Classification	6.2.1.2
Classification	Ligases Forming carbon-sulfur bonds Acid--thiol ligases
Catalyses reactions	ATP + Coenzyme A + Acid <-> Diphosphate + AMP + Acyl-CoA ATP + Coenzyme A + Butanoate <-> Diphosphate + AMP + Butanoyl-CoA ATP + Coenzyme A + Benzoate <-> Diphosphate + AMP + Benzoyl-CoA ATP + Coenzyme A + Decanoate <-> Diphosphate + AMP + Decanoyl-CoA ATP + Coenzyme A + Hexanoate <-> Diphosphate + AMP + Hexanoyl-CoA ATP + Coenzyme A + Dodecanoate <-> Diphosphate + AMP + Lauroyl-CoA ATP + Coenzyme A + Phenylacetic acid <-> Diphosphate + AMP + Phenylacetyl-CoA ATP + Coenzyme A + Salicylate <-> Diphosphate + AMP + Salicyl-CoA
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 6.2.1.2