Enzyme Details

Enzyme (Recommended) Name	long-chain-fatty-acid---CoA ligase
Alternative names	acyl-CoA ligase acid:CoA ligase (AMP-forming) acyl-CoA synthetase fatty acid thiokinase (long chain) acyl-activating enzyme palmitoyl-CoA synthase lignoceroyl-CoA synthase arachidonyl-CoA synthetase acyl coenzyme A synthetase palmitoyl coenzyme A synthetase thiokinase palmitoyl-CoA ligase acyl-coenzyme A ligase fatty acid CoA ligase long-chain fatty acyl coenzyme A synthetase oleoyl-CoA synthetase stearoyl-CoA synthetase long chain fatty acyl-CoA synthetase long-chain acyl CoA synthetase fatty acid elongase LCFA synthetase pristanoyl-CoA synthetase ACS3 long-chain acyl-CoA synthetase I long-chain acyl-CoA synthetase II fatty acyl-coenzyme A synthetase long-chain acyl-coenzyme A synthetase FAA1
EC Classification	6.2.1.3
Classification	Ligases Forming carbon-sulfur bonds Acid--thiol ligases
Catalyses reactions	ATP + Coenzyme A + Long-chain carboxylate <-> Diphosphate + AMP + Acyl-CoA ATP + Coenzyme A + Palmitate <-> Diphosphate + AMP + Palmitoyl-CoA ATP + Coenzyme A + Octanoate <-> Diphosphate + AMP + Octanoyl-CoA ATP + Coenzyme A + Oleate <-> Diphosphate + AMP + Oleoyl-CoA Oleate <-> Oleate ATP + Coenzyme A + Decanoate <-> Diphosphate + AMP + Decanoyl-CoA ATP + Coenzyme A + Dodecanoate <-> Diphosphate + AMP + Lauroyl-CoA ATP + Coenzyme A + Myristic acid <-> Diphosphate + AMP + Myristoyl-CoA ATP + Coenzyme A + Stearate <-> Diphosphate + AMP + Stearoyl-CoA ATP + Coenzyme A + 16-Hydroxyhexadecanoic acid <-> Diphosphate + AMP + 16-Hydroxypalmitoyl-CoA ATP + Coenzyme A + Hexanoate <-> Diphosphate + AMP + Hexanoyl-CoA ATP + Coenzyme A + Nonanoate <-> Diphosphate + AMP + Nonanoyl-CoA ATP + Coenzyme A + Arachidonate <-> Diphosphate + AMP + Arachidonyl-CoA ATP + Coenzyme A + Linoleate <-> Diphosphate + AMP + Linoleoyl-CoA
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 6.2.1.3