Enzyme Details

Enzyme (Recommended) Name	8-demethylnovobiocic acid synthase
Alternative names	Novobiocin ligase
EC Classification	6.3.1.15
Classification	Ligases Forming carbon-nitrogen bonds Acid-D-ammonia (or amine) ligases (amide synthases)
Catalyses reactions	ATP + 3-Amino-4,7-dihydroxy-8-methylcoumarin + 3-Methyl-4-hydroxybenzoate <-> Diphosphate + AMP + Novobiocic acid analog ATP + 3-Dimethylallyl-4-hydroxybenzoate + 3-Amino-4,7-dihydroxy-8-methylcoumarin <-> Diphosphate + AMP + Novobiocic acid
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 6.3.1.15