Enzyme Details

Enzyme (Recommended) Name	carnosine synthase
Alternative names	L-histidine:beta-alanine ligase (ADP-forming) carnosine synthetase carnosine-anserine synthetase homocarnosine-carnosine synthetase carnosine-homocarnosine synthetase L-histidine:beta-alanine ligase (AMP-forming) (incorrect)
EC Classification	6.3.2.11
Classification	Ligases Forming carbon-nitrogen bonds Acid--amino-acid ligases (peptide synthases)
Catalyses reactions	ATP + L-Lysine + beta-Alanine <-> Diphosphate + AMP + beta-Alanyl-L-lysine ATP + L-Arginine + beta-Alanine <-> Diphosphate + AMP + beta-Alanyl-L-arginine ATP + L-Histidine + beta-Alanine <-> Diphosphate + AMP + Carnosine ATP + L-Histidine + 4-Aminobutanoate <-> Diphosphate + AMP + Homocarnosine ATP + beta-Alanine + N(pai)-Methyl-L-histidine <-> H2O + Diphosphate + AMP + beta-Alanyl-N(pai)-methyl-L-histidine ATP + beta-Alanine + N(pai)-Methyl-L-histidine <-> Diphosphate + AMP + beta-Alanyl-N(pai)-methyl-L-histidine ATP + L-Histidine + beta-Alanine <-> ADP + Phosphate + Carnosine ATP + L-Histidine + 4-Aminobutanoate <-> ADP + Phosphate + Homocarnosine ATP + L-Lysine + beta-Alanine <-> ADP + Phosphate + beta-Alanyl-L-lysine ATP + L-Ornithine + beta-Alanine <-> ADP + Phosphate + beta-Alanyl-L-ornithine ATP + beta-Alanine + N(pai)-Methyl-L-histidine <-> ADP + Phosphate + beta-Alanyl-N(pai)-methyl-L-histidine
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 6.3.2.11