Enzyme Details

Enzyme (Recommended) Name	5-formyltetrahydrofolate cyclo-ligase
Alternative names	5-formyltetrahydrofolate cyclo-ligase (ADP-forming) 5,10-methenyltetrahydrofolate synthetase formyltetrahydrofolic cyclodehydrase 5-formyltetrahydrofolate cyclodehydrase
EC Classification	6.3.3.2
Classification	Ligases Forming carbon-nitrogen bonds Cyclo-ligases
Catalyses reactions	ATP + 5-Formyltetrahydrofolate <-> ADP + Phosphate + 5,10-Methenyltetrahydrofolate ATP + (6S)-5-Formyltetrahydrofolyl-glutamate <-> ADP + Phosphate + 5,10-Methenyltetrahydrofolyl-glutamate ATP + 5-Formyltetrahydrofolyl-[Glu](5) <-> ADP + Phosphate + 5,10-Methenyltetrahydrofolyl-[Glu](5) ATP + 5-Formyltetrahydrofolyl-glutamate <-> ADP + Phosphate + 5,10-Methenyltetrahydrofolyl-glutamate
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 6.3.3.2