Enzyme Details

Enzyme (Recommended) Name	formate---tetrahydrofolate ligase
Alternative names	formate:tetrahydrofolate ligase (ADP-forming) formyltetrahydrofolate synthetase 10-formyltetrahydrofolate synthetase tetrahydrofolic formylase tetrahydrofolate formylase
EC Classification	6.3.4.3
Classification	Ligases Forming carbon-nitrogen bonds Other carbon--nitrogen ligases
Catalyses reactions	ATP + Formate + 5,6,7,8-Tetrahydrofolate <-> ADP + Phosphate + 10-Formyltetrahydrofolate ATP + Formate + 5,6,7,8-Tetrahydropteroylpentaglutamate <-> ADP + Phosphate + 10-Formyltetrahydrofolylpentaglutamate
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 6.3.4.3