Enzyme Details

Enzyme (Recommended) Name	hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)
Alternative names	hydrogenobyrinic-acid:L-glutamine amido-ligase (AMP-forming) CobB
EC Classification	6.3.5.9
Classification	Ligases Forming carbon-nitrogen bonds Carbon--nitrogen ligases with glutamine as amido-N-donor
Catalyses reactions	2 ATP + 2 H2O + 2 L-Glutamine + Hydrogenobyrinate <-> 2 ADP + 2 Phosphate + 2 L-Glutamate + Hydrogenobyrinate a,c diamide ATP + H2O + L-Glutamine + Hydrogenobyrinate c-monoamide <-> ADP + Phosphate + L-Glutamate + Hydrogenobyrinate a,c diamide ATP + H2O + NH3 + Hydrogenobyrinate c-monoamide <-> ADP + Phosphate + Hydrogenobyrinate a,c diamide 2 ATP + 2 H2O + 2 Glutamine + (CN,aq)Cobyrinate <-> 2 ADP + 2 Phosphate + 2 Glutamate + (CN,aq)Cobyrinate a,c-diamide ATP + H2O + Glutamine + (CN,aq)Cobyrinate c-monoamide <-> ADP + Phosphate + Glutamate + (CN,aq)Cobyrinate a,c-diamide
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 6.3.5.9