Pathway Details

Recommended name

Limonene and pinene degradation

Alternative names

Reactions

H+ + NADPH + O2 + (-)-Limonene <-> H2O + NADP+ + (-)-trans-Carveol

H+ + NADPH + O2 + (-)-Limonene <-> H2O + NADP+ + Perillyl alcohol

NADP+ + (-)-trans-Carveol <-> H+ + NADPH + (-)-Carvone

NAD+ + Perillyl alcohol <-> NADH + H+ + Perillyl aldehyde

alpha-Pinene-oxide <-> (Z)-2-Methyl-5-isopropylhexa-2,5-dienal

H2O + Limonene-1,2-epoxide <-> Limonene-1,2-diol

NAD+ + (+)-trans-Carveol <-> NADH + H+ + (+)-(S)-Carvone

H+ + NADPH + O2 + (+)-Limonene <-> H2O + NADP+ + (+)-trans-Carveol

NAD+ + H2O + Perillyl aldehyde <-> NADH + H+ + Perillic acid

ATP + Coenzyme A + Perillic acid <-> ADP + Phosphate + H2O + Perillyl-CoA

ATP + Coenzyme A + Perillic acid <-> H2O + Diphosphate + AMP + Perillyl-CoA

H2O + Perillyl-CoA <-> 2-Hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA

Acceptor + 2-Hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA <-> Reduced acceptor + 4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA

H2O + 4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA <-> 3-Isopropenylpimelyl-CoA

H+ + (+)-(S)-Carvone <-> (1R,4S)-Iso-dihydrocarvone

H+ + (-)-Carvone <-> (1R,4R)-Dihydrocarvone

(4R,6R)-cis-Carveol <-> (-)-Carvone

(4S,6S)-cis-Carveol <-> (+)-(S)-Carvone

(1R,2R,4R)-Dihydrocarveol <-> (1R,4R)-Dihydrocarvone

(1R,2R,4S)-Iso-dihydrocarveol <-> (1R,4S)-Iso-dihydrocarvone

(1R,2S,4R)-Neo-dihydrocarveol <-> (1R,4R)-Dihydrocarvone

(1R,2S,4S)-Neoiso-dihydrocarveol <-> (1R,4S)-Iso-dihydrocarvone

(1R,4R)-Dihydrocarvone <-> (1S,4R)-Iso-dihydrocarvone

(1R,4S)-Iso-dihydrocarvone <-> (1S,4S)-Dihydrocarvone

(1S,2S,4R)-Iso-dihydrocarveol <-> (1S,4R)-Iso-dihydrocarvone

(1S,2S,4S)-Dihydrocarveol <-> (1S,4S)-Dihydrocarvone

(1S,2R,4R)-Neoiso-dihydrocarveol <-> (1S,4R)-Iso-dihydrocarvone

(1S,2R,4S)-Neo-dihydrocarveol <-> (1S,4S)-Dihydrocarvone

(1R,4R)-Dihydrocarvone <-> (4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone

(1R,4S)-Iso-dihydrocarvone <-> (4S,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone

(1S,4R)-Iso-dihydrocarvone <-> (3S,6R)-6-Isopropenyl-3-methyl-2-oxo-oxepanone

(1S,4S)-Dihydrocarvone <-> (3S,6S)-6-Isopropenyl-3-methyl-2-oxo-oxepanone

(4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone <-> (3R)-6-Hydroxy-3-isopropenyl-heptanoate

(3S,6R)-6-Isopropenyl-3-methyl-2-oxo-oxepanone <-> (5R)-6-Hydroxy-5-isopropenyl-2-methylhexanoate

(4S,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone <-> (3S)-6-Hydroxy-3-isopropenyl-heptanoate

(3S,6S)-6-Isopropenyl-3-methyl-2-oxo-oxepanone <-> (5S)-6-Hydroxy-5-isopropenyl-2-methylhexanoate

(3R)-6-Hydroxy-3-isopropenyl-heptanoate <-> (3R)-3-Isopropenyl-6-oxoheptanoate

(3S)-6-Hydroxy-3-isopropenyl-heptanoate <-> (3S)-3-Isopropenyl-6-oxoheptanoate

ATP + Coenzyme A + (3R)-3-Isopropenyl-6-oxoheptanoate <-> ADP + Phosphate + H2O + (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA

(3S)-3-Isopropenyl-6-oxoheptanoate <-> (3S)-3-Isopropenyl-6-oxoheptanoyl-CoA

NADH + H+ + O2 + (+)-Limonene <-> NAD+ + OH- + Limonene-1,2-epoxide

Limonene-1,2-diol <-> (1S,4R)-1-Hydroxy-2-oxolimonene

H+ + NADPH + O2 + (1S,4R)-1-Hydroxy-2-oxolimonene <-> OH- + NADP+ + (3R)-3-Isopropenyl-6-oxoheptanoate

Reduced acceptor + alpha-Pinene <-> H2O + Acceptor + Myrtenol

O2 + Acceptor + Myrtenol <-> 2 H2O + Reduced acceptor + Myrtenal

H2O + Acceptor + Myrtenal <-> Reduced acceptor + Myrtenic acid

H+ + O2 + alpha-Pinene <-> H2O + Pinocarveol

Pinocarveol <-> H+ + Pinocarvone

NADH + H+ + O2 + alpha-Pinene <-> NAD+ + H2O + alpha-Pinene-oxide

NAD+ + H2O + (Z)-2-Methyl-5-isopropylhexa-2,5-dienal <-> NADH + H+ + cis-2-Methyl-5-isopropylhexa-2,5-dienoic acid

NAD+ + H2O + trans-2-Methyl-5-isopropylhexa-2,5-dienal <-> NADH + H+ + trans-2-Methyl-5-isopropylhexa-2,5-dienoic acid

ATP + Coenzyme A + cis-2-Methyl-5-isopropylhexa-2,5-dienoic acid <-> Phosphate + AMP + cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA

ATP + Coenzyme A + trans-2-Methyl-5-isopropylhexa-2,5-dienoic acid <-> Phosphate + AMP + trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA

H2O + cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA <-> 3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA

H2O + trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA <-> 3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA

NAD+ + 3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA <-> NADH + H+ + 2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA

Coenzyme A + 2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA <-> Propanoyl-CoA + 3-Isopropylbut-3-enoyl-CoA

H2O + 3-Isopropylbut-3-enoyl-CoA <-> Coenzyme A + 3-Isopropylbut-3-enoic acid

ATP + Coenzyme A + (3R)-3-Isopropenyl-6-oxoheptanoate <-> H2O + Diphosphate + AMP + (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA

H+ + NADPH + O2 + (4R)-Dihydrocarvone <-> H2O + NADP+ + (4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone

Classification

Metabolism of Terpenoids and Polyketides