Pathway Details

 Recommended name Puromycin biosynthesis
 Alternative names
 Reactions
ATP + NAD+ <-> NADH + H+ + 3'-Keto-3'-deoxy-ATP
3'-Keto-3'-deoxy-ATP <-> Diphosphate + 3'-Keto-3'-deoxy-AMP
3'-Keto-3'-deoxy-AMP <-> 3'-Amino-3'-deoxy-AMP
Tyrosine + 3'-Amino-3'-deoxy-AMP <-> N6,N6,O-Trimethylpuromycin-5'-phosphate
Acetyl-CoA + N6,N6,O-Trimethylpuromycin-5'-phosphate <-> Coenzyme A + N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate
S-Adenosyl-L-methionine + N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate <-> S-Adenosyl-L-homocysteine + N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate
S-Adenosyl-L-methionine + N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate <-> S-Adenosyl-L-homocysteine + N-Acetyl-O-demethylpuromycin-5'-phosphate
N-Acetyl-O-demethylpuromycin-5'-phosphate <-> N-Acetyl-O-demethylpuromycin
S-Adenosyl-L-methionine + N-Acetyl-O-demethylpuromycin <-> S-Adenosyl-L-homocysteine + N-Acetylpuromycin
H2O + N-Acetylpuromycin <-> Acetate + Puromycin
 Classification
Biosynthesis of Other Secondary Metabolites
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