Pathway Details
Recommended name
Phenylalanine, tyrosine and tryptophan biosynthesis
Alternative names
Reactions
ATP + L-Tyrosine + tRNA(Tyr) <-> Diphosphate + AMP + L-Tyrosyl-tRNA(Tyr)
ATP + L-Phenylalanine + tRNA(Phe) <-> Diphosphate + AMP + L-Phenylalanyl-tRNA(Phe)
L-Serine + Indole <-> H2O + L-Tryptophan
NAD+ + H2O + L-Phenylalanine <-> NADH + H+ + NH3 + Phenylpyruvate
H2O + L-Phenylalanine + O2 <-> NH3 + H2O2 + Phenylpyruvate
L-Arogenate <-> H2O + L-Phenylalanine + CO2
Pyruvate + L-Phenylalanine <-> L-Alanine + Phenylpyruvate
L-Phenylalanine + 2-Oxoglutarate <-> L-Glutamate + Phenylpyruvate
H2O + L-Tyrosine + O2 <-> NH3 + H2O2 + 3-(4-Hydroxyphenyl)pyruvate
NAD+ + L-Arogenate <-> NADH + H+ + L-Tyrosine + CO2
NADP+ + L-Arogenate <-> H+ + L-Tyrosine + NADPH + CO2
L-Tyrosine + 2-Oxoglutarate <-> L-Glutamate + 3-(4-Hydroxyphenyl)pyruvate
NH3 + Chorismate <-> Pyruvate + H2O + Anthranilate
L-Glutamine + Chorismate <-> Pyruvate + L-Glutamate + Anthranilate
Diphosphate + N-(5-Phospho-D-ribosyl)anthranilate <-> 5-Phospho-alpha-D-ribose 1-diphosphate + Anthranilate
Prephenate <-> H2O + CO2 + Phenylpyruvate
3-Dehydroshikimate <-> H2O + 3,4-Dihydroxybenzoate
5-O-(1-Carboxyvinyl)-3-phosphoshikimate <-> Phosphate + Chorismate
Chorismate <-> Prephenate
NAD+ + Prephenate <-> NADH + H+ + CO2 + 3-(4-Hydroxyphenyl)pyruvate
NADP+ + Prephenate <-> H+ + NADPH + CO2 + 3-(4-Hydroxyphenyl)pyruvate
Oxaloacetate + L-Arogenate <-> L-Aspartate + Prephenate
L-Phenylalanine + O2 + Tetrahydrobiopterin <-> H2O + L-Tyrosine + 6,7-Dihydrobiopterin
Phosphoenolpyruvate + H2O + D-Erythrose 4-phosphate <-> Phosphate + 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate
NAD+ + Quinate <-> NADH + H+ + 3-Dehydroquinate
PQQ + Quinate <-> 3-Dehydroquinate + PQQH2
ATP + Shikimate <-> ADP + Shikimate 3-phosphate
NADP+ + Shikimate <-> H+ + NADPH + 3-Dehydroshikimate
PQQ + Shikimate <-> PQQH2 + 3-Dehydroshikimate
L-Serine + (3-Indolyl)-glycerol phosphate <-> H2O + L-Tryptophan + Glyceraldehyde 3-phosphate
2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate <-> Phosphate + 3-Dehydroquinate
3-Dehydroquinate <-> H2O + 3-Dehydroshikimate
Phosphoenolpyruvate + Shikimate 3-phosphate <-> Phosphate + 5-O-(1-Carboxyvinyl)-3-phosphoshikimate
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate <-> H2O + CO2 + (3-Indolyl)-glycerol phosphate
NADP+ + Quinate <-> H+ + NADPH + 3-Dehydroquinate
NAD+ + Shikimate <-> NADH + H+ + 3-Dehydroshikimate
NAD+ + H2O + L-Tyrosine <-> NADH + H+ + NH3 + 3-(4-Hydroxyphenyl)pyruvate
L-Serine + (3-Indolyl)-glycerol phosphate <-> D-Glyceraldehyde 3-phosphate + H2O + L-Tryptophan
2-Oxoglutarate + L-Arogenate <-> L-Glutamate + Prephenate
(3-Indolyl)-glycerol phosphate <-> D-Glyceraldehyde 3-phosphate + Indole
Pyruvate + L-Tyrosine <-> L-Alanine + 3-(4-Hydroxyphenyl)pyruvate
NAD+ + (-)-Shikimate <-> NADH + H+ + (-)-3-Dehydroshikimate
N-(5-Phospho-D-ribosyl)anthranilate <-> 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
Classification
Amino Acid Metabolism
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