Pathway Details
Recommended name
Fatty acid biosynthesis
Alternative names
Reactions
ATP + Acetyl-CoA + Hydrogencarbonate <-> ADP + Phosphate + Malonyl-CoA
ATP + Coenzyme A + Long-chain carboxylate <-> Diphosphate + AMP + Acyl-CoA
ATP + Coenzyme A + Palmitate <-> Diphosphate + AMP + Palmitoyl-CoA
NAD+ + Acyl-[acyl-carrier protein] <-> NADH + H+ + trans-2,3-Dehydroacyl-[acyl-carrier protein]
NADP+ + Acyl-[acyl-carrier protein] <-> H+ + NADPH + trans-2,3-Dehydroacyl-[acyl-carrier protein]
Acetyl-CoA + Holo-[acyl-carrier protein] <-> Coenzyme A + Acetyl-[acyl-carrier protein]
Malonyl-CoA + Holo-[acyl-carrier protein] <-> Coenzyme A + Malonyl-[acyl-carrier protein]
H2O + Hexadecanoyl-[acp] <-> Palmitate + Holo-[acyl-carrier protein]
2-Methylpropanoyl-CoA <-> Branched chain fatty acid
NADP+ + (3R)-3-Hydroxyacyl-[acyl-carrier protein] <-> H+ + NADPH + 3-Oxoacyl-[acyl-carrier protein]
Acyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <-> CO2 + Holo-[acyl-carrier protein] + 3-Oxoacyl-[acyl-carrier protein]
H2O + Oleoyl-[acyl-carrier protein] <-> Oleate + Holo-[acyl-carrier protein]
O2 + Reduced acceptor + Stearoyl-[acyl-carrier protein] <-> 2 H2O + Acceptor + Oleoyl-[acyl-carrier protein]
H2O + Dodecanoyl-[acyl-carrier protein] <-> Holo-[acyl-carrier protein] + Dodecanoate
3-Methylbutanoyl-CoA <-> Branched chain fatty acid
Malonyl-[acyl-carrier protein] + Acetyl-[acyl-carrier protein] <-> CO2 + Holo-[acyl-carrier protein] + Acetoacetyl-[acp]
ATP + Hydrogencarbonate + Holo-[carboxylase] <-> ADP + Phosphate + Carboxybiotin-carboxyl-carrier protein
Acetyl-CoA + Carboxybiotin-carboxyl-carrier protein <-> Malonyl-CoA + Holo-[carboxylase]
(3R)-3-Hydroxybutanoyl-[acyl-carrier protein] <-> H2O + But-2-enoyl-[acyl-carrier protein]
NAD+ + Butyryl-[acp] <-> NADH + H+ + But-2-enoyl-[acyl-carrier protein]
NADP+ + Butyryl-[acp] <-> H+ + NADPH + But-2-enoyl-[acyl-carrier protein]
NADP+ + (3R)-3-Hydroxybutanoyl-[acyl-carrier protein] <-> H+ + NADPH + Acetoacetyl-[acp]
NADP+ + (3R)-3-Hydroxydecanoyl-[acyl-carrier protein] <-> H+ + NADPH + 3-Oxodecanoyl-[acp]
(3R)-3-Hydroxydecanoyl-[acyl-carrier protein] <-> H2O + trans-Dec-2-enoyl-[acp]
NADP+ + (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] <-> H+ + NADPH + 3-Oxooctanoyl-[acp]
(3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] <-> H2O + trans-Oct-2-enoyl-[acp]
NADP+ + (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] <-> H+ + NADPH + 3-Oxohexadecanoyl-[acp]
(3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] <-> H2O + trans-Hexadec-2-enoyl-[acp]
NADP+ + (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] <-> H+ + NADPH + 3-Oxotetradecanoyl-[acp]
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] <-> H2O + trans-Tetradec-2-enoyl-[acp]
NAD+ + Dodecanoyl-[acyl-carrier protein] <-> NADH + H+ + trans-Dodec-2-enoyl-[acp]
NADP+ + Dodecanoyl-[acyl-carrier protein] <-> H+ + NADPH + trans-Dodec-2-enoyl-[acp]
Malonyl-[acyl-carrier protein] + Dodecanoyl-[acyl-carrier protein] <-> CO2 + Holo-[acyl-carrier protein] + 3-Oxotetradecanoyl-[acp]
Malonyl-[acyl-carrier protein] + Butyryl-[acp] <-> CO2 + Holo-[acyl-carrier protein] + 3-Oxohexanoyl-[acp]
NADP+ + (R)-3-Hydroxyhexanoyl-[acp] <-> H+ + NADPH + 3-Oxohexanoyl-[acp]
(R)-3-Hydroxyhexanoyl-[acp] <-> H2O + trans-Hex-2-enoyl-[acp]
NAD+ + Hexanoyl-[acp] <-> NADH + H+ + trans-Hex-2-enoyl-[acp]
NADP+ + Hexanoyl-[acp] <-> H+ + NADPH + trans-Hex-2-enoyl-[acp]
Malonyl-[acyl-carrier protein] + Hexanoyl-[acp] <-> CO2 + Holo-[acyl-carrier protein] + 3-Oxooctanoyl-[acp]
NAD+ + Octanoyl-[acp] <-> NADH + H+ + trans-Oct-2-enoyl-[acp]
NADP+ + Octanoyl-[acp] <-> H+ + NADPH + trans-Oct-2-enoyl-[acp]
Malonyl-[acyl-carrier protein] + Octanoyl-[acp] <-> CO2 + Holo-[acyl-carrier protein] + 3-Oxodecanoyl-[acp]
NAD+ + Decanoyl-[acp] <-> NADH + H+ + trans-Dec-2-enoyl-[acp]
NADP+ + Decanoyl-[acp] <-> H+ + NADPH + trans-Dec-2-enoyl-[acp]
Malonyl-[acyl-carrier protein] + Decanoyl-[acp] <-> CO2 + Holo-[acyl-carrier protein] + 3-Oxododecanoyl-[acp]
NADP+ + (R)-3-Hydroxydodecanoyl-[acp] <-> H+ + NADPH + 3-Oxododecanoyl-[acp]
(R)-3-Hydroxydodecanoyl-[acp] <-> H2O + trans-Dodec-2-enoyl-[acp]
NAD+ + Tetradecanoyl-[acp] <-> NADH + H+ + trans-Tetradec-2-enoyl-[acp]
NADP+ + Tetradecanoyl-[acp] <-> H+ + NADPH + trans-Tetradec-2-enoyl-[acp]
Malonyl-[acyl-carrier protein] + Tetradecanoyl-[acp] <-> CO2 + Holo-[acyl-carrier protein] + 3-Oxohexadecanoyl-[acp]
NAD+ + Hexadecanoyl-[acp] <-> NADH + H+ + trans-Hexadec-2-enoyl-[acp]
NADP+ + Hexadecanoyl-[acp] <-> H+ + NADPH + trans-Hexadec-2-enoyl-[acp]
H+ + 2n NADPH + Acetyl-CoA + n Malonyl-CoA <-> 2n NADP+ + n+1 Coenzyme A + n CO2 + Long-chain fatty acid
14 H+ + 14 NADPH + Acetyl-CoA + 7 Malonyl-CoA <-> 14 NADP+ + 8 Coenzyme A + 7 CO2 + Palmitate
H+ + 2n NADPH + n Malonyl-CoA + Butanoyl-CoA <-> 2n NADP+ + n+1 Coenzyme A + n CO2 + Long-chain fatty acid
H+ + 2n NADPH + n Malonyl-CoA + Propanoyl-CoA <-> 2n NADP+ + n+1 Coenzyme A + n CO2 + Long-chain fatty acid
H+ + 2n NADPH + n Malonyl-CoA + Hexanoyl-CoA <-> 2n NADP+ + n+1 Coenzyme A + n CO2 + Long-chain fatty acid
H+ + 2n NADPH + n Malonyl-CoA + Octanoyl-CoA <-> 2n NADP+ + n+1 Coenzyme A + n CO2 + Long-chain fatty acid
Malonyl-[acyl-carrier protein] + Hexadecanoyl-[acp] <-> CO2 + Holo-[acyl-carrier protein] + 3-Oxooctadecanoyl-[acp]
Classification
Lipid Metabolism
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