Pathway Details

 Recommended name Biosynthesis of nucleotide sugars
 Alternative names
 Reactions
NAD+ + H2O + CDP-4-dehydro-3,6-dideoxy-D-glucose <-> NADH + H+ + CDP-4-dehydro-6-deoxy-D-glucose
L-Glutamine + D-Fructose 6-phosphate <-> L-Glutamate + D-Glucosamine 6-phosphate
ATP + Glucose <-> ADP + Glucose 6-phosphate
GTP + L-Fucose 1-phosphate <-> Diphosphate + GDP-L-fucose
D-Arabinose 5-phosphate <-> D-Ribulose 5-phosphate
CTP + D-Glucose 1-phosphate <-> Diphosphate + CDPglucose
ATP + L-Fucose <-> ADP + L-Fucose 1-phosphate
NAD+ + GDP-6-deoxy-D-talose <-> NADH + H+ + GDP-4-dehydro-D-rhamnose
Acetyl-CoA + D-Glucosamine 6-phosphate <-> Coenzyme A + N-Acetyl-D-glucosamine 6-phosphate
2 NAD+ + H2O + UDP-N-acetyl-D-glucosamine <-> 2 NADH + 2 H+ + UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate
ATP + D-Mannose <-> ADP + D-Mannose 6-phosphate
Phosphate + N-Acetylneuraminate 9-phosphate <-> Phosphoenolpyruvate + H2O + N-Acetyl-D-mannosamine 6-phosphate
Phosphate + 3-Deoxy-D-manno-octulosonate 8-phosphate <-> Phosphoenolpyruvate + H2O + D-Arabinose 5-phosphate
S-Adenosyl-L-methionine + dTDP-3-amino-2,3,6-trideoxy-D-threo-hexopyranos-4-ulose <-> S-Adenosyl-L-homocysteine + dTDP-3-amino-2,3,6-trideoxy-C-methyl-D-erythro-hexopyranos-4-ulose
dTDP-4-dehydro-6-deoxy-D-glucose <-> dTDP-4-dehydro-beta-L-rhamnose
Sedoheptulose 7-phosphate <-> D-Glycero-D-manno-heptose 7-phosphate
alpha-D-Glucose + (Phosphate)n <-> alpha-D-Glucose 6-phosphate + (Phosphate)n
2 NAD+ + H2O + GDP-D-mannose <-> 2 NADH + 2 H+ + GDP-D-mannuronate
UDP-3-ketoglucose <-> UDP-kanosamine
UDP-L-arabinose <-> UDPxylose
CTP + N-Acetylneuraminate <-> Diphosphate + CMP-N-acetylneuraminate
4,6-Dideoxy-4-oxo-dTDP-D-glucose <-> dTDP-4-dehydro-beta-L-rhamnose
GTP + D-Mannose 1-phosphate <-> Diphosphate + GDPmannose
D-Mannose 6-phosphate <-> beta-D-Fructose 6-phosphate
UDP-D-glucose <-> UDP-D-galactose
H2O + UDP-N-acetyl-D-glucosamine <-> UDP + N-Acetyl-D-mannosamine
2 NAD+ + H2O + UDPgalactose <-> 2 NADH + 2 H+ + UDP-D-galacturonate
2 NAD+ + H2O + UDPglucose <-> 2 NADH + H+ + UDPglucuronate
alpha-D-Glucose 6-phosphate <-> beta-D-Fructose 6-phosphate
ATP + D-Galactose <-> ADP + alpha-D-Galactose 1-phosphate
dTDPglucose <-> H2O + 4,6-Dideoxy-4-oxo-dTDP-D-glucose
dTDP-D-glucose <-> H2O + dTDP-4-dehydro-6-deoxy-D-glucose
UTP + N-Acetyl-alpha-D-glucosamine 1-phosphate <-> Diphosphate + UDP-N-acetyl-D-glucosamine
UDP-D-glucose + alpha-D-Galactose 1-phosphate <-> UDP-D-galactose + alpha-D-Glucose 1-phosphate
Diphosphate + UDP-D-galacturonate <-> UTP + D-Galacturonate 1-phosphate
UDPgalactose <-> UDP-D-galacto-1,4-furanose
UDPglucuronate <-> UDP-D-galacturonate
dTDP-4-oxo-2,6-dideoxy-D-allose <-> dTDP-4-oxo-2,6-dideoxy-L-mannose
2 NAD+ + H2O + GDPmannose <-> 2 NADH + 2 H+ + GDP-D-mannuronate
ATP + D-Glucose 1-phosphate <-> Diphosphate + ADP alpha-D-glucoside
Phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine <-> Phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine
NADP+ + UDP-N-acetylmuramate <-> H+ + NADPH + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine
O2 + myo-Inositol <-> H2O + D-Glucuronate
ATP + L-Arabinose <-> ADP + beta-L-Arabinose 1-phosphate
UTP + 1-Phospho-alpha-D-glucuronate <-> Diphosphate + UDPglucuronate
alpha-D-Glucose 1-phosphate <-> alpha-D-Glucose 6-phosphate
GDPmannose <-> H2O + GDP-4-dehydro-D-rhamnose
UTP + D-Glucose 1-phosphate <-> Diphosphate + UDPglucose
2 NAD+ + H2O + UDP-D-galactose <-> 2 NADH + 2 H+ + UDP-D-galacturonate
GDP-D-mannose <-> H2O + n+1 GDP-4-dehydro-D-rhamnose
dTDP-L-4-oxovancosamine <-> dTDP-L-vancosamine
ADP-D-glycero-D-manno-heptose <-> ADP-L-glycero-D-manno-heptose
ATP + D-Glucosamine <-> ADP + D-Glucosamine 6-phosphate
UDP-N-acetyl-D-glucosamine <-> UDP-N-acetyl-D-mannosamine
NADP+ + GDP-D-rhamnose <-> H+ + NADPH + GDP-4-dehydro-D-rhamnose
dTDP-4-amino-4,6-dideoxy-D-galactose + 2-Oxoglutarate <-> L-Glutamate + dTDP-4-dehydro-6-deoxy-D-galactose
dTDP-4-oxo-6-deoxy-D-allose <-> dTDP-6-deoxy-D-allose
UDPglucuronate <-> CO2 + UDP-D-xylose
CDP-3,6-dideoxy-D-glucose <-> CDP-3,6-dideoxy-D-mannose
CTP + 3-Deoxy-D-manno-octulosonate <-> Diphosphate + CMP-3-deoxy-D-manno-octulosonate
GTP + D-Glucose 1-phosphate <-> Diphosphate + GDPglucose
dTDPglucose <-> H2O + dTDP-4-dehydro-6-deoxy-D-glucose
UDP-N-acetyl-D-glucosamine <-> UDP-N-acetyl-D-galactosamine
L-Glutamate + 3,6-Dideoxy-3-oxo-dTDP-D-glucose <-> 2-Oxoglutarate + dTDP-3-amino-3,6-dideoxy-D-glucose
2 NAD+ + H2O + UDP-N-acetyl-D-mannosamine <-> 2 NADH + 2 H+ + UDP-N-acetyl-D-mannosaminouronate
2 S-Adenosyl-L-methionine + dTDP-3-amino-3,4,6-trideoxy-D-glucose <-> 2 S-Adenosyl-L-homocysteine + dTDP-D-desosamine
D-Glucose 1-phosphate + dTTP <-> Diphosphate + dTDPglucose
H2O + NADP+ + CDP-4-dehydro-3,6-dideoxy-D-glucose <-> H+ + NADPH + CDP-4-dehydro-6-deoxy-D-glucose
ATP + D-Glucuronate <-> ADP + D-Glucuronate 1-phosphate
UDP-L-arabinose <-> UDP-D-xylose
ATP + alpha-D-Glucose <-> alpha-D-Glucose 6-phosphate + ADP
NAD+ + GDP-D-rhamnose <-> NADH + H+ + GDP-4-dehydro-D-rhamnose
2 H+ + O2 + 2 Ferrocytochrome b5 + CMP-N-acetylneuraminate <-> H2O + 2 Ferricytochrome b5 + CMP-N-glycoloylneuraminate
UDPglucose <-> UDPgalactose
UTP + alpha-D-Glucose 1-phosphate <-> Diphosphate + UDP-D-glucose
D-Glucosamine 1-phosphate <-> D-Glucosamine 6-phosphate
H2O + N-Acetylneuraminate 9-phosphate <-> Phosphate + N-Acetylneuraminate
NADP+ + CDP-3,6-dideoxy-D-glucose <-> H+ + NADPH + CDP-4-dehydro-3,6-dideoxy-D-glucose
GTP + D-Mannose 1-phosphate <-> Diphosphate + GDP-D-mannose
dTDP-L-rhamnose <-> dTDP-L-dihydrostreptose
UDP-D-glucose <-> H2O + UDP-4-dehydro-6-deoxy-D-glucose
4,6-Dideoxy-4-oxo-dTDP-D-glucose <-> dTDP-4-oxo-6-deoxy-D-allose
dTDP-3-amino-2,3,6-trideoxy-C-methyl-D-erythro-hexopyranos-4-ulose <-> dTDP-L-4-oxovancosamine
ATP + D-Glucuronate <-> ADP + 1-Phospho-alpha-D-glucuronate
GDP-D-mannose <-> GDP-L-galactose
CTP + alpha-D-Glucose 1-phosphate <-> Diphosphate + CDPglucose
NADP+ + GDP-L-fucose <-> H+ + NADPH + GDP-4-dehydro-D-rhamnose
GTP + alpha-D-Glucose 1-phosphate <-> Diphosphate + GDPglucose
UDPglucuronate <-> CO2 + UDPapiose
2 S-Adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-D-glucose <-> 2 H+ + 2 S-Adenosyl-L-homocysteine + dTDP-D-mycaminose
ATP + N-Acetyl-D-mannosamine <-> ADP + N-Acetyl-D-mannosamine 6-phosphate
ATP + D-Glycero-D-manno-heptose 7-phosphate <-> ADP + D-Glycero-D-manno-heptose 1,7-bisphosphate
D-Glucose 1-phosphate <-> alpha-D-Glucose 6-phosphate
ATP + D-Galacturonate <-> ADP + D-Galacturonate 1-phosphate
dTDP-D-glucose <-> H2O + 4,6-Dideoxy-4-oxo-dTDP-D-glucose
H2O + D-Glycero-D-manno-heptose 1,7-bisphosphate <-> Phosphate + D-Glycero-D-manno-heptose 1-phosphate
4,6-Dideoxy-4-oxo-dTDP-D-glucose <-> 3,6-Dideoxy-3-oxo-dTDP-D-glucose
2 NAD+ + H2O + UDP-N-acetyl-D-galactosamine <-> 2 NADH + 2 H+ + UDP-N-acetyl-D-galactosaminuronic acid
H2O + 3-Deoxy-D-manno-octulosonate 8-phosphate <-> Phosphate + 3-Deoxy-D-manno-octulosonate
NAD+ + UDPglucuronate <-> NADH + H+ + CO2 + UDP-beta-L-threo-pentapyranos-4-ulose
UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose + 2-Oxoglutarate <-> L-Glutamate + UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose
NAD+ + UDP-D-glucose <-> NADH + H+ + UDP-3-ketoglucose
ATP + alpha-D-Glucose 1-phosphate <-> Diphosphate + ADP alpha-D-glucoside
2 S-Adenosyl-L-methionine + dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose <-> 2 S-Adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,4,6-trideoxy-D-glucose
UDP-D-galactose <-> UDP-D-galacto-1,4-furanose
2 NAD+ + H2O + UDP-D-glucose <-> 2 NADH + H+ + UDPglucuronate
ATP + D-Glycero-D-manno-heptose 1-phosphate <-> Diphosphate + ADP-D-glycero-D-manno-heptose
D-Mannose 6-phosphate <-> D-Mannose 1-phosphate
GDPmannose <-> GDP-L-galactose
UDPglucose <-> H2O + UDP-4-dehydro-6-deoxy-D-glucose
alpha-D-Galactose 1-phosphate + UDPglucose <-> D-Glucose 1-phosphate + UDPgalactose
UDPglucuronate <-> CO2 + UDPxylose
Phosphate + N-Acetylneuraminate <-> Phosphoenolpyruvate + H2O + N-Acetyl-D-mannosamine
UTP + D-Glucuronate 1-phosphate <-> Diphosphate + UDPglucuronate
NADP+ + dTDP-L-rhamnose <-> H+ + NADPH + dTDP-4-dehydro-beta-L-rhamnose
NADP+ + GDP-6-deoxy-D-talose <-> H+ + NADPH + GDP-4-dehydro-D-rhamnose
alpha-D-Glucose 1-phosphate + dTTP <-> Diphosphate + dTDP-D-glucose
dTDP-4-amino-4,6-dideoxy-D-glucose + 2-Oxoglutarate <-> L-Glutamate + dTDP-4-dehydro-6-deoxy-D-glucose
NADP+ + dTDP-D-fucose <-> H+ + NADPH + 4,6-Dideoxy-4-oxo-dTDP-D-glucose
Acetyl-CoA + dTDP-4-amino-4,6-dideoxy-D-glucose <-> Coenzyme A + dTDP-4-acetamido-4,6-dideoxy-D-glucose
ATP + D-Glucose <-> ADP + Glucose 6-phosphate
L-Glutamate + dTDP-3-oxo-4,6-dideoxy-D-glucose <-> dTDP-3-amino-3,4,6-trideoxy-D-glucose + 2-Oxoglutarate
ATP + beta-D-Fructose <-> beta-D-Fructose 6-phosphate + ADP
ATP + N-Acetyl-D-glucosamine <-> ADP + N-Acetyl-D-glucosamine 6-phosphate
CDPglucose <-> H2O + CDP-4-dehydro-6-deoxy-D-glucose
ATP + D-Glucose <-> ADP + D-Glucose 6-phosphate
NAD+ + UDPglucose <-> NADH + H+ + UDP-3-ketoglucose
dTDP-4-dehydro-6-deoxy-D-glucose <-> dTDP-3-oxo-6-deoxy-D-glucose
 Classification
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