Reaction Details
Reaction ID
122
Stochiometric Equation
10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <-> 5,6,7,8-Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
Substrates
10-Formyltetrahydrofolate
1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
Products
5,6,7,8-Tetrahydrofolate
1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
Enzymes known to
catalyse this reaction
(curated information)
EC Number
in Organism
UniProtKB Link
PubMedID
2.1.2.3
Gallus gallus
UniProtKB
1937050
2.1.2.3
Homo sapiens
UniProtKB
14966129
Pathways
Biosynthesis of secondary metabolites
Metabolic pathways
One carbon pool by folate
Purine metabolism
External Links
KEGG-Pathway-ID
map01110
map01100
map00670
map00230
KEGG-Reaction-ID
R04560
MetaNetX-Reaction-ID
MNXR95639
Rhea-Reaction-ID
22192
22193
22194
22195
Reactome-Reaction-ID
R-DME-73798
R-HSA-73798
R-XTR-73798
R-BTA-73798
R-SSC-73798
R-CFA-73798
R-RNO-73798
R-OSA-73798
R-TGU-73798
R-DDI-73798
R-GGA-419254
R-SPO-73798
R-SCE-73798
R-ATH-73798
R-DRE-73798
R-GGA-73798
R-MMU-73798
View all entries for reaction 10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <-> 5,6,7,8-Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
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