Reaction Details

Reaction ID

1451

Stochiometric Equation

NAD+ + Glycine + 5,6,7,8-Tetrahydrofolate <-> NADH + H+ + CO2 + NH3 + 5,10-Methylenetetrahydrofolate

Substrates

5,6,7,8-Tetrahydrofolate

Glycine

NAD+

Products

NH3

H+

NADH

CO2

5,10-Methylenetetrahydrofolate

Enzymes known to
catalyse this reaction
(curated information)

EC Number	in Organism	UniProtKB Link	PubMedID
2.1.2.10	Pisum sativum	UniProtKB	16667685
Complex: 1.4.4.2 / 1.8.1.4 / 2.1.2.10	Canis familiaris	UniProtKB	10347152
Complex: 1.4.4.2 / 1.8.1.4 / 2.1.2.10	Homo sapiens	UniProtKB	10347152
Complex: 1.4.4.2 / 1.8.1.4 / 2.1.2.10	Oryctolagus cuniculus	UniProtKB	10347152
Complex: 1.4.4.2 / 1.8.1.4 / 2.1.2.10	Rattus norvegicus	UniProtKB	10347152
Complex: 1.4.4.2 / 2.1.2.10 / 1.8.1.4	Pisum sativum	UniProtKB	3080433

Pathways

Biosynthesis of secondary metabolites
Carbon metabolism
Glyoxylate and Dicarboxylate metabolism
Metabolic pathways
Nitrogen metabolism

External Links

KEGG-Pathway-ID

map01110
map01200
map00630
map01100
map00910

KEGG-Reaction-ID

R01221

MetaNetX-Reaction-ID

MNXR100330

Rhea-Reaction-ID

27761 27760 27759 27758