Reaction Details

Reaction ID

15085

Stochiometric Equation

H+ + NADPH + 2-Oxoglutarate <-> NADP+ + 2-Hydroxyglutarate

Substrates

2-Oxoglutarate

NADPH

H+

Products

2-Hydroxyglutarate

NADP+

Enzymes known to
catalyse this reaction
(curated information)

EC Number	in Organism	UniProtKB Link	PubMedID
1.1.1.42	Escherichia coli	UniProtKB	27406240
1.1.1.42	Homo sapiens	UniProtKB	20142433
1.1.1.42	Homo sapiens	UniProtKB	25502799
1.1.1.42	Homo sapiens	UniProtKB	26436839
1.1.1.42	Mycobacterium tuberculosis	UniProtKB	23409873
1.1.1.42	Saccharomyces cerevisiae	UniProtKB	25502799
1.1.1.42	Yarrowia lipolytica	UniProtKB	25502799

MetaNetX-Reaction-ID

MNXR169840

Rhea-Reaction-ID

52311 52310 52308 52309