Reaction Details



 Reaction ID 6061
 Stochiometric Equation 7 Malonyl-CoA + 2-Methylpropanoyl-CoA + 5 2-Methylmalonyl-CoA <-> 13 Coenzyme A + 12 CO2 + 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2b'' aglycone
 Substrates
Malonyl-CoA
2-Methylpropanoyl-CoA
2-Methylmalonyl-CoA
 Products
Coenzyme A
CO2
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2b'' aglycone
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
 Pathways Biosynthesis of 12-, 14- and 16-membered macrolides


View all entries for reaction 7 Malonyl-CoA + 2-Methylpropanoyl-CoA + 5 2-Methylmalonyl-CoA <-> 13 Coenzyme A + 12 CO2 + 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2b'' aglycone

© HITS gGmbH