Reaction Details

Stochiometric Equation H+ + NADPH + O2 + Cyclophosphamide <-> H2O + NADP+ + 4-Hydroxycyclophosphamide
Substrates
H+
NADPH
O2
Cyclophosphamide
Products
H2O
NADP+
4-Hydroxycyclophosphamide
Enzymes known to catalyse this reaction (curated information)
EC Numberin OrganismUniProt LinkPubMedID
1.14.14.1 Canis familiaris UniProt 27015760
1.14.14.1 Homo sapiens UniProt 27015760
Pathways Drug metabolism - cytochrome P450


View all entries for reaction H+ + NADPH + O2 + Cyclophosphamide <-> H2O + NADP+ + 4-Hydroxycyclophosphamide