Reaction Details

Stochiometric Equation NADP+ + 5-Methyltetrahydrofolate <-> H+ + NADPH + 5,10-Methylenetetrahydrofolate
Substrates
NADP+
5-Methyltetrahydrofolate
Products
H+
5,10-Methylenetetrahydrofolate
NADPH
Enzymes known to catalyse this reaction (curated information)
EC Numberin OrganismUniProt LinkPubMedID
1.5.1.20 Homo sapiens UniProt 2383427
1.5.1.20 Saccharomyces cerevisiae UniProt 11729203
1.5.1.20 Sus scrofa UniProt 6975779
Pathways Metabolic pathways
Methane metabolism
Microbial metabolism in diverse environments
One carbon pool by folate


View all entries for reaction NADP+ + 5-Methyltetrahydrofolate <-> H+ + NADPH + 5,10-Methylenetetrahydrofolate