Reaction Details

Stochiometric Equation H+ + 2n NADPH + Acetyl-CoA + n Malonyl-CoA <-> 2n NADP+ + n+1 Coenzyme A + n CO2 + Long-chain fatty acid
Substrates
NADPH
Acetyl-CoA
Malonyl-CoA
H+
Products
CO2
NADP+
Long-chain fatty acid
Coenzyme A
Enzymes known to catalyse this reaction (curated information)
EC Numberin OrganismUniProt LinkPubMedID
2.3.1.38 Rattus norvegicus UniProt 15715522
2.3.1.85 Gallus gallus UniProt 7044669
2.3.1.85 Homo sapiens UniProt 16215233
2.3.1.85 Homo sapiens UniProt 7567999
2.3.1.85 Rattus norvegicus UniProt 7044669
2.3.1.86 Saccharomyces cerevisiae UniProt 7044669
Pathways Fatty acid biosynthesis


View all entries for reaction H+ + 2n NADPH + Acetyl-CoA + n Malonyl-CoA <-> 2n NADP+ + n+1 Coenzyme A + n CO2 + Long-chain fatty acid