Reaction Details

Stochiometric Equation NADP+ + 5,10-Methylenetetrahydrofolate <-> H+ + NADPH + 5,10-Methenyltetrahydrofolate
Substrates
NADP+
5,10-Methylenetetrahydrofolate
Products
5,10-Methenyltetrahydrofolate
NADPH
H+
Enzymes known to catalyse this reaction (curated information)
EC Numberin OrganismUniProt LinkPubMedID
1.5.1.15 Homo sapiens UniProt 8218174
1.5.1.5 Escherichia coli UniProt 1748668
1.5.1.5 Leishmania major UniProt 19183277
1.5.1.5 Photobacterium phosphoreum UniProt 8765228
1.5.1.5 Sus scrofa UniProt 6607769
1.5.1.5 Sus scrofa UniProt 838698
Pathways Biosynthesis of cofactors
Carbon fixation pathways in prokaryotes
Carbon metabolism
Glyoxylate and Dicarboxylate metabolism
Metabolic pathways
Microbial metabolism in diverse environments
One carbon pool by folate


View all entries for reaction NADP+ + 5,10-Methylenetetrahydrofolate <-> H+ + NADPH + 5,10-Methenyltetrahydrofolate