Reaction Details

Stochiometric Equation 5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + Dihydrofolate
Substrates
dUMP
5,10-Methylenetetrahydrofolate
Products
dTMP
Dihydrofolate
Enzymes known to catalyse this reaction (curated information)
EC Numberin OrganismUniProt LinkPubMedID
2.1.1.45 Bacillus subtilis UniProt 418407
2.1.1.45 Bacteriophage T4 UniProt 2271601
2.1.1.45 Crithidia fasciculata UniProt 14696
2.1.1.45 Escherichia coli UniProt 10704192
2.1.1.45 Escherichia coli UniProt 10841779
2.1.1.45 Escherichia coli UniProt 14967040
2.1.1.45 Escherichia coli UniProt 26612036
2.1.1.45 Escherichia coli UniProt 3286637
2.1.1.45 Escherichia coli UniProt 42538
2.1.1.45 Homo sapiens UniProt 12859954
2.1.1.45 Homo sapiens UniProt 2656695
2.1.1.45 Homo sapiens UniProt 269853
2.1.1.45 Homo sapiens UniProt 34155
2.1.1.45 Lactobacillus casei UniProt 10704192
2.1.1.45 Lactobacillus casei UniProt 10964985
2.1.1.45 Lactobacillus casei UniProt 1284431
2.1.1.45 Lactobacillus casei UniProt 1606134
2.1.1.45 Lactobacillus casei UniProt 1627545
2.1.1.45 Lactobacillus casei UniProt 2153960
2.1.1.45 Lactobacillus casei UniProt 2182628
2.1.1.45 Lactobacillus casei UniProt 413834
2.1.1.45 Lactobacillus casei UniProt 8180187
2.1.1.45 Lactobacillus casei UniProt 8378336
2.1.1.45 Lactobacillus casei UniProt 9383465
2.1.1.45 Lactobacillus casei UniProt 9398324
2.1.1.45 Leishmania major UniProt 3597407
2.1.1.45 Leishmania major UniProt 8144647
2.1.1.45 Leishmania tropica UniProt 3922404
2.1.1.45 Rattus norvegicus UniProt 3567221
2.1.1.45 Toxoplasma gondii UniProt 12192007
2.1.1.45 Trypanosoma cruzi UniProt 14696
2.1.1.45 Trypanosoma cruzi UniProt 7969266
Pathways Folate biosynthesis
Metabolic pathways
One carbon pool by folate
Pyrimidine metabolism


View all entries for reaction 5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + Dihydrofolate