Reaction Details
Stochiometric Equation
5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + Dihydrofolate
Substrates
dUMP
5,10-Methylenetetrahydrofolate
Products
dTMP
Dihydrofolate
Enzymes known to catalyse this reaction (curated information)
EC Number
in Organism
UniProt Link
PubMedID
2.1.1.45
Bacillus subtilis
UniProt
418407
2.1.1.45
Bacteriophage T4
UniProt
2271601
2.1.1.45
Crithidia fasciculata
UniProt
14696
2.1.1.45
Escherichia coli
UniProt
10704192
2.1.1.45
Escherichia coli
UniProt
10841779
2.1.1.45
Escherichia coli
UniProt
14967040
2.1.1.45
Escherichia coli
UniProt
26612036
2.1.1.45
Escherichia coli
UniProt
3286637
2.1.1.45
Escherichia coli
UniProt
42538
2.1.1.45
Homo sapiens
UniProt
12859954
2.1.1.45
Homo sapiens
UniProt
2656695
2.1.1.45
Homo sapiens
UniProt
269853
2.1.1.45
Homo sapiens
UniProt
34155
2.1.1.45
Lactobacillus casei
UniProt
10704192
2.1.1.45
Lactobacillus casei
UniProt
10964985
2.1.1.45
Lactobacillus casei
UniProt
1284431
2.1.1.45
Lactobacillus casei
UniProt
1606134
2.1.1.45
Lactobacillus casei
UniProt
1627545
2.1.1.45
Lactobacillus casei
UniProt
2153960
2.1.1.45
Lactobacillus casei
UniProt
2182628
2.1.1.45
Lactobacillus casei
UniProt
413834
2.1.1.45
Lactobacillus casei
UniProt
8180187
2.1.1.45
Lactobacillus casei
UniProt
8378336
2.1.1.45
Lactobacillus casei
UniProt
9383465
2.1.1.45
Lactobacillus casei
UniProt
9398324
2.1.1.45
Leishmania major
UniProt
3597407
2.1.1.45
Leishmania major
UniProt
8144647
2.1.1.45
Leishmania tropica
UniProt
3922404
2.1.1.45
Rattus norvegicus
UniProt
3567221
2.1.1.45
Toxoplasma gondii
UniProt
12192007
2.1.1.45
Trypanosoma cruzi
UniProt
14696
2.1.1.45
Trypanosoma cruzi
UniProt
7969266
Pathways
Folate biosynthesis
Metabolic pathways
One carbon pool by folate
Pyrimidine metabolism
View all entries for reaction 5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + Dihydrofolate