| EC Classification |
1.1.1.51
|
Enzyme name
(recommended) |
3(or 17)beta-hydroxysteroid dehydrogenase |
| Alternative names |
3(or 17)beta-hydroxysteroid:NAD(P)+ oxidoreductase
beta-hydroxy steroid dehydrogenase
17-ketoreductase
17beta-hydroxy steroid dehydrogenase
3beta-hydroxysteroid dehydrogenase
17beta-hydroxy steroid dehydrogenase
3beta-hydroxy steroid dehydrogenase
|
| Classification |
| Oxidoreductases |
| Acting on the CH-OH group of donors |
| With NAD(+) or NADP(+) as acceptor |
|
| Catalyses reactions
|
| NAD+ + Testosterone <-> NADH + H+ + Androst-4-ene-3,17-dione |
| NADP+ + Testosterone <-> H+ + NADPH + Androst-4-ene-3,17-dione |
| NAD+ + 20alpha-Hydroxy-4-pregnen-3-one <-> NADH + H+ + Progesterone |
| NAD+ + Estradiol-17beta <-> NADH + H+ + Estrone |
| NADP+ + Estradiol-17beta <-> H+ + NADPH + Estrone |
| NAD+ + 1-Propanol <-> NADH + H+ + Propanal |
| NAD+ + 5alpha-Androstane-3alpha-ol-17-one <-> NADH + H+ + 5alpha-Androstane-3,17-dione |
| NAD+ + Cortisol <-> NADH + H+ + Cortisone |
| NAD+ + 17alpha,20alpha-Dihydroxypregn-4-en-3-one <-> NADH + H+ + 17alpha-Hydroxyprogesterone |
| NAD+ + Androst-5-ene-3beta,17beta-diol <-> NADH + H+ + 3beta-Hydroxyandrost-5-en-17-one |
| NADP+ + Androst-5-ene-3beta,17beta-diol <-> H+ + NADPH + 3beta-Hydroxyandrost-5-en-17-one |
| NAD+ + 3alpha-Hydroxy-5beta-androstan-17-one <-> NADH + H+ + 5beta-Androstane-3,17-dione |
| NAD+ + 3alpha-Hydroxy-5beta-pregnane-20-one <-> NADH + H+ + 5beta-Pregnane-3,20-dione |
| NADH + H+ + 5alpha-Androstane-17beta-ol-3-one <-> NAD+ + 5alpha-Androstane-3alpha,17beta-diol |
| NADH + H+ + Cyclohex-2-enone <-> NAD+ + Cyclohex-2-en-1-ol |
| NAD+ + (S)-Indan-1-ol <-> NADH + H+ + Indanone |
| NADH + H+ + p-Nitrobenzaldehyde <-> NAD+ + p-Nitrobenzyl alcohol |
| NADH + H+ + 9,10-Phenanthroquinone <-> NAD+ + Phenanthrene-9,10-diol |
| NADH + H+ + Prostaglandin D2 <-> NAD+ + 9alpha,11beta-Prostaglandin F2 |
| NADH + H+ + 4-Chlorobenzaldehyde <-> NAD+ + p-Chlorobenzyl alcohol |
| H+ + NADPH + 4-Chlorobenzaldehyde <-> NADP+ + p-Chlorobenzyl alcohol |
| NADH + H+ + 5alpha-Androstane-3alpha-ol-17-one <-> NAD+ + 5alpha-Androstane-3alpha,17beta-diol |
| NAD+ + 5alpha-Androstane-17beta-ol-3-one <-> NADH + H+ + 5alpha-Androstane-3,17-dione |
| NAD+ + 5beta-Androstane-3alpha,17beta-diol <-> NADH + H+ + 3alpha-Hydroxy-5beta-androstan-17-one |
| NAD+ + 5beta-Androstane-17beta-ol-3-one <-> NADH + H+ + 5beta-Androstane-3,17-dione |
| NADH + H+ + 21-Dehydrocortisol <-> NAD+ + Cortisol |
| H+ + NADPH + 6-tert-Butyl-2,3-epoxy-5-cyclohexene-1,4-dione <-> NADP+ + 6-tert-Butyl-2,3-epoxy-4(R)-hydroxy-5-cyclohexene-1-one |
| H+ + NADPH + t-Butyl-p-benzoquinone <-> NADP+ + t-Butyl-p-hydrobenzoquinone |
| NADH + H+ + 6-tert-Butyl-2,3-epoxy-5-cyclohexene-1,4-dione <-> NAD+ + 6-tert-Butyl-2,3-epoxy-4(R)-hydroxy-5-cyclohexene-1-one |
| H+ + NADPH + 6-tert-Butyl-2,3-epoxy-5-cyclohexene-1,4-dione <-> NADP+ + 6-tert-Butyl-2,3-epoxy-4-hydroxy-5-cyclohexene-1-one |
| NADP+ + (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol <-> H+ + NADPH + (S)-(+)-2,3,4-Trihydro-1-naphtone |
| NAD+ + (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol <-> NADH + H+ + (S)-(+)-2,3,4-Trihydro-1-naphtone |
| 2 NAD+ + trans-Cyclohexa-3,5-diene-1,2-diol <-> 2 NADH + 2 H+ + 2-Hydroxycyclohexa-3,5-diene-1-one |
| NAD+ + alpha-3-Hydroxyhexobarbital <-> NADH + H+ + 3-Oxohexobarbital |
| NAD+ + beta-3-Hydroxyhexobarbital <-> NADH + H+ + 3-Oxohexobarbital |
| NAD+ + 9alpha,11alpha-Prostaglandin F2 <-> NADH + H+ + Prostaglandin D2 |
| NADH + H+ + Isatin <-> NAD+ + 2,3-Dihydroxyindole |
| 2 NADH + 2 H+ + (1S)-(+)-Camphorquinone <-> 2 NAD+ + 1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol |
| 2 NADH + 2 H+ + (1R)-(-)-Camphorquinone <-> 2 NAD+ + 1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol |
| NADH + H+ + 6-tert-Butyl-2,3-epoxy-5-cyclohexene-1,4-dione <-> NAD+ + 6-tert-Butyl-2,3-epoxy-4-hydroxy-5-cyclohexene-1-one |
| 2 NADH + 2 H+ + 2,3-Pentanedione <-> 2 NAD+ + 2,3-Pentanediol |
| 2 NADH + 2 H+ + Dimethylglyoxal <-> 2 NAD+ + 2,3-Butanediol |
| NAD+ + 20alpha-Hydroxy-5alpha-pregnan-3-one <-> NADH + H+ + 5alpha-Pregnane-3,20-dione |
| NAD+ + 4-Androsten-3alpha-ol-17-one <-> NADH + H+ + Androst-4-ene-3,17-dione |
| NADH + H+ + 4-Androsten-3alpha-ol-17-one <-> NAD+ + Androst-4-ene-3alpha,17beta-diol |
| NADH + H+ + 5beta-Pregnane-3,20-dione <-> NAD+ + 20alpha-Hydroxy-5beta-pregnan-3-one |
| NADH + H+ + 20alpha-Hydroxy-5beta-pregnan-3-one <-> NAD+ + Pregnanediol |
| NADH + H+ + 16-Ketoestrone <-> NAD+ + 16-Hydroxyestrone |
|
| External links
|
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
|
|
View all entries for EC Class:
1.1.1.51
|
