Reaction Details

Reaction ID

2300

Stochiometric Equation

NAD+ + Estradiol-17beta <-> NADH + H+ + Estrone

Substrates

NAD+

Estradiol-17beta

Products

NADH

Estrone

H+

Enzymes known to
catalyse this reaction
(curated information)

EC Number	in Organism	UniProtKB Link	PubMedID
1.1.1.210	Homo sapiens	UniProtKB	22437839
1.1.1.239	Mesocricetus auratus	UniProtKB	2317205
1.1.1.357	Homo sapiens	UniProtKB	22437839
1.1.1.51	Homo sapiens	UniProtKB	10329704
1.1.1.51	Rattus norvegicus	UniProtKB	16788056
1.1.1.62	Homo sapiens	UniProtKB	12943747
1.1.1.62	Homo sapiens	UniProtKB	8099587
1.1.1.62	Mus musculus	UniProtKB	9712896

Pathways

Metabolic pathways
Steroid hormone biosynthesis

External Links

KEGG-Pathway-ID

map01100
map00140

KEGG-Reaction-ID

R02352

MetaNetX-Reaction-ID

MNXR145253

Rhea-Reaction-ID

24615 24613 24614 24612