Enzyme Details

 EC Classification 1.2.1.25
 Enzyme name
(recommended)		 2-oxoisovalerate dehydrogenase (acylating)
 Alternative names 3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)
2-oxoisovalerate dehydrogenase
alpha-ketoisovalerate dehydrogenase
 Classification
Oxidoreductases
Acting on the aldehyde or oxo group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
NAD+ + Coenzyme A + alpha-Ketovaline <-> NADH + H+ + CO2 + 2-Methylpropanoyl-CoA
NAD+ + Coenzyme A + 4-Methyl-2-oxopentanoate <-> NADH + H+ + CO2 + 3-Methylbutanoyl-CoA
NAD+ + Coenzyme A + 3-Methyl-2-oxopentanoate <-> NADH + H+ + CO2 + 2-Methylbutanoyl-CoA
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.2.1.25



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