Enzyme Details
EC Classification
1.4.1.20
Enzyme name
(recommended)
phenylalanine dehydrogenase
Alternative names
L-phenylalanine:NAD+ oxidoreductase (deaminating)
L-phenylalanine dehydrogenase
PHD
Classification
Oxidoreductases
Acting on the CH-NH(2) group of donors
With NAD(+) or NADP(+) as acceptor
Catalyses reactions
NAD+ + H2O + L-Phenylalanine <-> NADH + H+ + NH3 + Phenylpyruvate
NAD+ + H2O + L-Leucine <-> NADH + H+ + NH3 + 4-Methyl-2-oxopentanoate
NAD+ + H2O + L-Valine <-> NADH + H+ + NH3 + alpha-Ketovaline
NAD+ + H2O + L-Isoleucine <-> NADH + H+ + NH3 + (R)-2-Oxo-3-methylpentanoate
NAD+ + H2O + L-Methionine <-> NADH + H+ + NH3 + 4-Methylthio-2-oxobutanoate
NAD+ + H2O + L-Norleucine <-> NADH + H+ + NH3 + 2-Oxohexanoate
NAD+ + H2O + L-Norvaline <-> NADH + H+ + NH3 + 2-Oxopentanoate
NAD+ + H2O + L-Tyrosine <-> NADH + H+ + NH3 + 3-(4-Hydroxyphenyl)pyruvate
NAD+ + H2O + L-Isoleucine <-> NADH + H+ + NH3 + 3-Methyl-2-oxopentanoate
NAD+ + H2O + L-Ethionine <-> NADH + NH3 + 4-Ethylthio-2-oxobutanoate
External links
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
View all entries for EC Class:
1.4.1.20
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