Enzyme Details

 EC Classification 1.4.1.8
 Enzyme name
(recommended)		 valine dehydrogenase (NADP+)
 Alternative names L-valine:NADP+ oxidoreductase (deaminating)
valine dehydrogenase (nicotinanide adenine dinucleotide phosphate)
valine dehydrogenase (NADP+)
 Classification
Oxidoreductases
Acting on the CH-NH(2) group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
NAD+ + H2O + L-Alanine <-> Pyruvate + NADH + H+ + NH3
NAD+ + H2O + L-Leucine <-> NADH + H+ + NH3 + 4-Methyl-2-oxopentanoate
H2O + L-Valine + NADP+ <-> H+ + NADPH + NH3 + alpha-Ketovaline
NAD+ + H2O + L-Valine <-> NADH + H+ + NH3 + alpha-Ketovaline
NAD+ + H2O + L-Norleucine <-> NADH + H+ + NH3 + 2-Oxohexanoate
NAD+ + H2O + L-Norvaline <-> NADH + H+ + NH3 + 2-Oxopentanoate
NAD+ + H2O + L-Isoleucine <-> NADH + H+ + NH3 + 3-Methyl-2-oxopentanoate
NAD+ + H2O + L-alpha-Aminobutyrate <-> NADH + H+ + NH3 + 2-Oxobutyrate
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.4.1.8



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