Enzyme Details

 EC Classification 1.5.1.33
 Enzyme name
(recommended)
pteridine reductase
 Alternative names 5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase
PTR1
pteridine reductase 1
 Classification
Oxidoreductases
Acting on the CH-NH group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
2 NADP+ + Tetrahydrobiopterin <-> 2 H+ + 2 NADPH + Biopterin
H+ + NADPH + 6,7-Dihydrobiopterin <-> NADP+ + Tetrahydrobiopterin
H+ + NADPH + 7,8-Dihydrobiopterin <-> NADP+ + Tetrahydrobiopterin
2 NADP+ + 5,6,7,8-Tetrahydrofolate <-> 2 H+ + 2 NADPH + Folate
NADP+ + Dihydrofolate <-> H+ + NADPH + Folate
oNADP+ + Pteridine reductase <-> inactivated Pteridine reductase
NADPH + Pteridine reductase <-> Enzyme-ligand complex
NADP+ + Pteridine reductase <-> Enzyme-ligand complex
NADH + Pteridine reductase <-> Enzyme-ligand complex
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.5.1.33



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