Reaction Details

Reaction ID

7757

Stochiometric Equation

H+ + NADPH + 7,8-Dihydrobiopterin <-> NADP+ + Tetrahydrobiopterin

Substrates

H+

7,8-Dihydrobiopterin

NADPH

Products

NADP+

Tetrahydrobiopterin

Enzymes known to
catalyse this reaction
(curated information)

EC Number	in Organism	UniProtKB Link	PubMedID
1.5.1.3	Bos taurus	UniProtKB	2322563
1.5.1.3	Rattus norvegicus	UniProtKB	962851
1.5.1.33	Leishmania major	UniProtKB	21239486
1.5.1.33	Leishmania tarentolae	UniProtKB	10415124
1.5.1.33	Leishmania tarentolae	UniProtKB	9186479
1.5.1.33	Trypanosoma brucei	UniProtKB	21239486

Pathways

Folate biosynthesis

MetaNetX-Reaction-ID

MNXR152295