Enzyme Details

EC Classification

3.1.4.11

Enzyme name
(recommended)

phosphoinositide phospholipase C

Alternative names

1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase
triphosphoinositide phosphodiesterase
phosphoinositidase C
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
monophosphatidylinositol phosphodiesterase
phosphatidylinositol phospholipase C
PI-PLC
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase

Classification

Hydrolases

Acting on ester bonds

Phosphoric diester hydrolases

Catalyses reactions

H2O + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <-> 1,2-Diacyl-sn-glycerol + D-myo-Inositol 1,4,5-trisphosphate

H2O + D-myo-Inositol 1,2-cyclic phosphate <-> D-myo-Inositol 1,4,5-trisphosphate

H2O + Phosphatidylinositol <-> Diacylglycerol + 1D-myo-Inositol 1-phosphate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 3.1.4.11