Reaction Details
Reaction ID
3231
Stochiometric Equation
H2O + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <-> 1,2-Diacyl-sn-glycerol + D-myo-Inositol 1,4,5-trisphosphate
Substrates
H2O
1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
Products
1,2-Diacyl-sn-glycerol
D-myo-Inositol 1,4,5-trisphosphate
Enzymes known to
catalyse this reaction
(curated information)
EC Number
in Organism
UniProtKB Link
PubMedID
3.1.4.11
Bos taurus
UniProtKB
8519600
3.1.4.11
Homo sapiens
UniProtKB
10336610
3.1.4.11
Homo sapiens
UniProtKB
8519600
3.1.4.11
Mammalia
UniProtKB
15709770
3.1.4.11
Oryctolagus cuniculus
UniProtKB
214133
3.1.4.11
Rattus norvegicus
UniProtKB
15322077
3.1.4.11
Rattus norvegicus
UniProtKB
8519600
3.1.4.11
Rattus norvegicus
UniProtKB
9565585
Pathways
Inositol phosphate metabolism
Metabolic pathways
Phosphatidylinositol signaling system
External Links
KEGG-Pathway-ID
map00562
map01100
map04070
KEGG-Reaction-ID
R03435
MetaNetX-Reaction-ID
MNXR148157
Rhea-Reaction-ID
33179
33181
33182
33180
MetaCyc-Reaction-ID
3.1.4.11-RXN
View all entries for reaction H2O + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <-> 1,2-Diacyl-sn-glycerol + D-myo-Inositol 1,4,5-trisphosphate
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