Enzyme Details

Enzyme (Recommended) Name	kynurenine 3-monooxygenase
Alternative names	L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating) kynurenine 3-hydroxylase kynurenine hydroxylase L-kynurenine-3-hydroxylase
EC Classification	1.14.13.9
Classification	Oxidoreductases Acting on paired donors with incorporation of molecular oxygen With NADH or NADPH as one donor, and incorporation of one atom of oxygen
Catalyses reactions	H+ + NADPH + O2 + L-Kynurenine <-> H2O + NADP+ + 3-Hydroxy-L-kynurenine NADH + H+ + O2 + L-Kynurenine <-> NAD+ + H2O + 3-Hydroxy-L-kynurenine L-Kynurenine + KMO-FAD <-> Enzyme-FAD-L-Kynurenine complex KMO-FAD + m-Nitrobenzoylalanine <-> Enzyme-FAD-m-Nitrobenzoylalanine complex
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.14.13.9