Reaction Details

Stochiometric Equation H+ + NADPH + O2 + L-Kynurenine <-> H2O + NADP+ + 3-Hydroxy-L-kynurenine
Substrates
H+
NADPH
L-Kynurenine
O2
Products
NADP+
H2O
3-Hydroxy-L-kynurenine
Enzymes known to catalyse this reaction (curated information)
EC Numberin OrganismUniProt LinkPubMedID
1.14.13.9 Cytophaga hutchinsonii UniProt 14700627
1.14.13.9 Homo sapiens UniProt 10672018
1.14.13.9 Homo sapiens UniProt 24316190
1.14.13.9 Homo sapiens UniProt 24381207
1.14.13.9 Homo sapiens UniProt 28604669
1.14.13.9 Pseudomonas fluorescens UniProt 16973376
1.14.13.9 Pseudomonas fluorescens UniProt 28604669
1.14.13.9 Rattus norvegicus UniProt 1332540
Pathways Biosynthesis of cofactors
Metabolic pathways
Tryptophan metabolism


View all entries for reaction H+ + NADPH + O2 + L-Kynurenine <-> H2O + NADP+ + 3-Hydroxy-L-kynurenine