Enzyme Details

Enzyme (Recommended) Name	squalene monooxygenase
Alternative names	squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) squalene epoxidase squalene-2,3-epoxide cyclase squalene 2,3-oxidocyclase squalene hydroxylase squalene oxydocyclase squalene-2,3-epoxidase
EC Classification	1.14.14.17
Classification	Oxidoreductases Acting on paired donors with incorporation of molecular oxygen With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Catalyses reactions	O2 + Reduced acceptor + Squalene <-> H2O + Acceptor + (S)-2,3-Epoxysqualene O2 + Reduced acceptor + Squalene <-> H2O + Acceptor + (S)-2,3-Epoxysqualene H+ + NADPH + O2 + Squalene <-> H2O + NADP+ + (S)-2,3-Epoxysqualene H+ + NADPH + O2 + (S)-2,3-Epoxysqualene <-> H2O + NADP+ + Diepoxysqualene NADH + H+ + O2 + Squalene <-> NAD+ + H2O + (S)-2,3-Epoxysqualene
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.14.14.17