Reaction Details

Stochiometric Equation H+ + NADPH + O2 + Squalene <-> H2O + NADP+ + (S)-2,3-Epoxysqualene
Substrates
H+
O2
NADPH
Squalene
Products
NADP+
H2O
(S)-2,3-Epoxysqualene
Enzymes known to catalyse this reaction (curated information)
EC Numberin OrganismUniProt LinkPubMedID
1.14.14.17 Homo sapiens UniProt 10666321
1.14.14.17 Homo sapiens UniProt 30626872
1.14.14.17 Rattus norvegicus UniProt 17112472
1.14.14.17 Rattus norvegicus UniProt 7595073
1.14.14.17 Saccharomyces cerevisiae UniProt 8358382
Pathways Biosynthesis of secondary metabolites
Metabolic pathways
Sesquiterpenoid and triterpenoid biosynthesis
Steroid biosynthesis


View all entries for reaction H+ + NADPH + O2 + Squalene <-> H2O + NADP+ + (S)-2,3-Epoxysqualene