Enzyme Details

Enzyme (Recommended) Name	pteridine reductase
Alternative names	5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase PTR1 pteridine reductase 1
EC Classification	1.5.1.33
Classification	Oxidoreductases Acting on the CH-NH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	2 NADP+ + Tetrahydrobiopterin <-> 2 H+ + 2 NADPH + Biopterin H+ + NADPH + 6,7-Dihydrobiopterin <-> NADP+ + Tetrahydrobiopterin H+ + NADPH + 7,8-Dihydrobiopterin <-> NADP+ + Tetrahydrobiopterin 2 NADP+ + 5,6,7,8-Tetrahydrofolate <-> 2 H+ + 2 NADPH + Folate NADP+ + Dihydrofolate <-> H+ + NADPH + Folate oNADP+ + Pteridine reductase <-> inactivated Pteridine reductase NADPH + Pteridine reductase <-> Enzyme-ligand complex NADP+ + Pteridine reductase <-> Enzyme-ligand complex NADH + Pteridine reductase <-> Enzyme-ligand complex
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.5.1.33